Journal article
Glucose Control Using a Standard vs. an Enhanced Hybrid Closed-Loop System-A Pilot Study
Barbora Paldus, Melissa H Lee, Hannah Jones, Sybil A Mcauley, Jodie C Horsburgh, Kerryn L Roem, Glenn Ward, Richard Macisaac, Neale Cohen, Peter G Colman, Alicia Jenkins, David N O'Neal
DIABETES | AMER DIABETES ASSOC | Published : 2018
DOI: 10.2337/db18-986-P
Abstract
Background: Hybrid closed loop (HCL) insulin delivery with the Medtronic MiniMed 670G system is safe and effective in improving glycemia for people with type 1 diabetes (T1D). Aims: To compare glucose control, CL exits and alarm frequency with standard HCL vs. enhanced HCL (eHCL) systems. Methods: Pump experienced adults with T1D (n=11; 9 women; mean[SD] age: 51[15]Y; HbA1c 7.5[1.0]%) were assigned in random order HCL and eHCL for 1 week each in a supervised live-in setting. eHCL incorporated enhanced bolus reminders and iterative changes broadening glucose and insulin delivery parameters permitting persistence in CL. For both HCL and eHCL insulin delivery was b..
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